The Speech-Language Pathologists’s Role in Understanding the Genetics of Van Der Woude Syndrome A family report of three generations of Van der Woude syndrome (cleft lip or palate and lip pits) is presented to show that the speech-language pathologist may play an important role in identifying patients with this defect. Understanding the genetic basis of this syndrome and documentation of family history through ... Articles
Articles  |   November 01, 1979
The Speech-Language Pathologists’s Role in Understanding the Genetics of Van Der Woude Syndrome
 
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Article Information
Articles   |   November 01, 1979
The Speech-Language Pathologists’s Role in Understanding the Genetics of Van Der Woude Syndrome
Journal of Speech and Hearing Disorders, November 1979, Vol. 44, 472-478. doi:10.1044/jshd.4404.472
History: Received December 22, 1978 , Accepted March 16, 1979
 
Journal of Speech and Hearing Disorders, November 1979, Vol. 44, 472-478. doi:10.1044/jshd.4404.472
History: Received December 22, 1978; Accepted March 16, 1979

A family report of three generations of Van der Woude syndrome (cleft lip or palate and lip pits) is presented to show that the speech-language pathologist may play an important role in identifying patients with this defect. Understanding the genetic basis of this syndrome and documentation of family history through pedigree analysis can be instrumental in identifying other family members potentially affected with speech disorders. Because the diagnosis of Van der Woude syndrome was made in one member of the family in the pedigree, three other family members who had never received previous diagnosis or treatment of their speech disorders were identified. Other family members were referred for genetic counseling. The concepts of autosomal dominant transmission, variable expression, incomplete penetrance, and the pedigree technique for recording family history are also presented.

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